Revolutionary QM212 Essay, Research Paper

Abstract:

A new process in bio-chemistry involves the manipulation of

molecules to defeat diseases, viruses, chemical warfare, and to reduce the

cost of bio-chemical engineering. This new process is refined in that the

researcher utilizes new computer technology to model the behavior of

certain molecules to insert a “slot” for discarding unwanted foreign

objects. These unwanted foreign objects are discarded by fixing the slot

to fit the objects. This slot can be customized, through manipulation and

modelling, to fit many different objects. Therefore, objects such as

viruses, poisonings, or bacteria, could be jetted out of ones body. This

aspect could one day benefit millions of people around the world.

Chemical Process:

Teams from universities successfully inserted instructions for

building an anti-fluorescein antibody in the DNA of bacteria. This

antibody binds with fluorescein molecules. Into this chunk of material,

they inserted instructions for buildin g a metal-ion binding sight. They

discovered where to put this slot by simulating the antibody on a large

computer. The resulting product revealed an anti-fluorescein antibody which

binds to metal ions. After physically inserting the genetic code in to E.

coli. bacteria, the researchers had a large batch of a new compound which

they named QM212. When copper was added to this new batch, it binded with

the metal-ion binding sight, decreasing the fluorescent emissions.

Applications:

The human immune system already uses similar antibodies for similar

tasks. Natural antibodies conform to the shape of foreign bodies and bind

to the outer surface. They then release enzymes to break down the

substance. In the experiment, c opper acted as the foreign body while

QM212 was the antibody.

One application of this process could be used by the military. The

military, utilizing bio-chemical tools, could engineer an antibody which

binds with nerve gas and splits each molecule. This could be accomplished

by first of all searching t he Brookhaven database for a proper antibody.

Then, using large mainframe computers, one can manipulate models of the

antibody and create a binding sight for the nerve gas molecules. Then, the

soldier would inject himself with the antibodies when h e is nerve gased.

Another application of this process could be used by bio? chemists

in fighting the AIDS epidemic. If an antibody was engineered to conform to

the AIDS virus, it could break it in half and dispose of it.

Finally, using E. coli., synthetic antibodies replacing current

vaccines could be mass produced. Instead of growing cultures of a disease

then killing them for use in vaccines, one could produce one antibody which

conforms to the disease the n reproduce this with E. Coli.

Impacts:

The impact of these applications could benefit people around the

world. Soldiers would not die (and continue killing like blind mice)

because of the nerve gas serum.

The AIDS epidemic would halt as announcements of a new product

which would desist the AIDS virus fill the radio waves. AIDS is

increasing exponentially and this would halt its fatal expansion. Also,

biologists would no longer waste money in replicating vaccines. A

mini-computer would be used to replicate synthetic antibodies instead.

Creating molecules with the uncanningly precise seek-and? destroy

capabilities of natural antibodies is an exciting step in replicating

nature’s fascinating immune system.

Bibliography

Uehling, Mark D. “Birth of a Molecule.” February 1992, p. 74